| 窦言东,王永春.化学通报,2025,88(6):659-664. |
| 几种碳-氟键构建的研究进展 |
| Research progress in the construction of C-F bonds |
| 投稿时间：2024-12-20 修订日期：2025-03-12 |
| DOI： |
| 中文关键词: 碳氟键 导向基 光催化 |
| 英文关键词:C-F bound Direct-group photo-catalyst |
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| 中文摘要: |
| 含氟化合物因其独特的化学性质使其在医药、农药和功能材料领域中有着广泛的应用。特别是将氟原子引入药物分子中后,会对药物的吸附、分布和代谢产生重大影响。近些年来,研究者对碳-氟键的构建做出了大量的研究工作,本文基于前人的研究成果,分别从脂肪链和芳基碳-氟键构建方式对近5年的工作进行总结和讨论。 |
| 英文摘要: |
| Fluorinated compounds have a wide range of applications in the fields of medicine, pesticides, and functional materials due to their unique chemical properties. Especially after introducing fluorine atoms into drug molecules, it will have a significant impact on the adsorption, distribution, and metabolism of drugs. In recent years, researchers have conducted extensive research on the construction of C-F bonds. Based on previous research results, this article summarizes and discusses the work in the past five years from the perspectives of C-F bond construction methods.on fatty chains and aromatic groups |
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